Biochemistry and Biophysics and Faramcology
 
Module: Basic Sciences
ECTS: 4
Contact hours – lectures: 50
Contact hours – seminar:  
Contact hours – clinical exercises: 20
Contact hours – clinical practice:  
Holder of subject: Dr Ivica Avberšek Lužnik, Assistant Professor
Year of study: First
 
Biochemistry and Biophysics

Contact hours – lectures: 25
Contact hours – seminar:  
Contact hours – clinical exercises: 10
Contact hours – clinical practice:  
Holder of subject: Dr Ivica Avberšek Lužnik, Assistant Professor
Education providers:
  • Dr Ivica Avberšek Lužnik, Assistant Professor
  • Dr Aleš Jerin, Assistant Professor
Level of study: First Bologna cycle professional education study program
Semester: Winter
Language: Slovene/English
 
Subject-specific competences: The student:
Gets a clear overview of the metabolic cycles and biochemistry as a science analysing the three-dimensional structure of biomolecules and communication between cells in an organism by also considering thermodynamics; learns the basic structural elements of living organisms and their physical and chemical interactions; learns the connection between structure and function of certain molecules; learns about the dynamic balance and interdependence of molecules in living organisms; learns about the main biochemical processes that take place in various cellular compartments.
Students will become familiar with the basic physical quantities and their roles in the human body.

Students will become acquainted with the main tasks of a diagnostic laboratory; especially the influence of errors in sample collection, the transportation and storage on laboratory samples and data interpretation will be explained in detail. The students will become familiar with the quality assurance system and with ethics in laboratory medicine. They will gain knowledge of the step-by-step laboratory diagnostic principle and learn about some basic screening tests and different sources of errors.

Knowledge and understanding:
Understanding overall molecular and pathophysiological processes in the human body.
Knowledge about essential areas of energetic metabolism and its integration into major pathways in the human body.
Knowledge about molecular structure of nucleic acids (DNA, RNA), gene expression and genetic diseases.
Knowledge about physiological chemistry, including cytochrome P450 enzymes, iron and heme metabolism, gas transport, pH regulation, digestion and absorption, and human nutrition from a biochemical perspective.
Knowledge about pathobiochemical background of diseases.
Knowledge about biochemical terminology in clinical settings.

Students will learn how to correctly handle different biological samples before laboratory analysis, how to perform some screening tests, and how to use different anticoagulants and other additives.
 
Mandatory references:
  • Boyer, R., 2005. Temelji biokemije. Ljubljana: Študentska založba.
  • Božič, B., Derganc, J., Gomišček, G., Kralj, V., Majhenc, J., Peterlin, P., Svetina, S. & Žekš, B., n.d. Praktikum iz biofizike. Available at: http://www.mf.uni-lj.si/ibf/prosto-dostopna-literatura.
Recommended references:  
Study obligations:
  • 50% obligatory attendance at lectures
Assessment methods:
  • written (60%)
  • oral examination (40%)